Synthesis of 5-Oxa-13-thiaprotoberberine Derivatives

Abstract
With phosgene or aliphatic aldehydes, 6,7-dimethoxy-2-(2-hydroxyphenyl)-3,4-dihydro-2H-1,3-benzothiazine afforded novel 10,11-dimethoxy-6H,8H,13aH[1,3]benzoxazino[4,3-b][1,3]benzothiazine derivatives, members of a new heterocyclic ring system.
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