Polymer Bound 3,5-Cyclohexadiene-1,2-diols as Core Structures for the Development of Small Molecule Libraries

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Abstract
A highly efficient sequence for the synthesis of complex, chiral and highly functionalized molecules on solid phase is reported. Solid phase bound cyclohexadiene-diols were derivatized through epoxidation, nucleophilic ring opening, Pd(0) cross-couplings and Diels-Alder reactions.

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