Anaerobic Replacement of Carbon Dioxide.

Abstract
Several compounds have been found which will replace CO2, necessary for the anaerobic metabolism of Escherichia coli and Aerobacter ae-rogenes. The C5 compounds appear to replace CO2 more effectively than other compounds tested with the exception of oxalacetic acid and citric acid, the latter in the case of A. aerogenes only. The fact that oxalacetic by-passes the CO2 requirement to such an extent indicates that this acid may function as the chief substrate for protein synthesis under anaerobic conditions.

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