Acarboxyprothrombin concentration [corrected] after oral prophylactic vitamin K.
Open Access
- 1 September 1987
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 62 (9) , 938-940
- https://doi.org/10.1136/adc.62.9.938
Abstract
The effect of prophylaxis with oral vitamin K (1 mg vitamin K1 given with the first feed) on the rate of detection of acarboxyprothrombin (PIVKA II) and factor II clotting concentration [corrected] were analysed. Introducing such prophylaxis reduced the rates of detection of PIVKA II concentration [corrected] on day 5 from 48% to zero. None of the babies given prophylaxis had factor II clotting concentration [corrected] below 40%, compared with 34 of 95 babies not given prophylaxis. This study has important implications in the prophylaxis of both classical and late onset haemorrhagic disease of the newborn.Keywords
This publication has 8 references indexed in Scilit:
- Use of oral vitamin K1 to prevent hemorrhagic disease of the newborn infantThe Journal of Pediatrics, 1986
- Vitamin K and Thrombotest values in full term infants.Archives of Disease in Childhood, 1986
- Plasma concentrations after oral or intramuscular vitamin K1 in neonates.Archives of Disease in Childhood, 1985
- Plasma concentrations after oral or intramuscular vitamin K1 in neonates.Archives of Disease in Childhood, 1985
- EFFECT OF VITAMIN K ADMINISTRATION ON ACARBOXY PROTHROMBIN (PIVKA-II) LEVELS IN NEWBORNSThe Lancet, 1985
- LATE ONSET HAEMORRHAGIC DISEASE OF NEWBORN WITH TEMPORARY MALABSORPTION OF VITAMIN K1The Lancet, 1985
- A Haematocrit Corrected Micro Determination of the P&P-Test and Blood Clotting Factors in Capillary BloodThrombosis and Haemostasis, 1974
- Hemorrhage in the newborn and vitamin K prophylaxisThe Journal of Pediatrics, 1962