New Cytotoxic Aristolactams from Pararistolochia flos-avis

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Abstract
Two new aristolactams, aristolactam-F1 [1] and -FIi[2], were isolated from active extracts of Paraistolochia flos-avis. their structures were elucidated on the basis of nmr, ms, uv, and ir spectral data. Aristolactam-1 [3] and -All [4] were also isolated from this plant. Aristolactam-AII showed cytotoxicity against PS and KB cells in culture.