COMPARATIVE-STUDY OF THE DIAGNOSTIC-VALUE OF DISK-ELECTROPHORESIS OF URINARY PROTEINS AND MEASUREMENT OF THE EXCRETION OF N-ACETYLGLUCOSAMINIDASE FOR THE DETECTION OF RENAL TUBULE DAMAGE IN CHRONIC POLYARTHRITIS

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 18  (1) , 53-58
Abstract
A method is described for the determination of N-acetyl-.beta.-D-glucosaminidase in gel-filtered urine. The individual reaction parameters were tested and the reliability of the method was determined. The stability of the enzyme in urine was investigated at different temperatures over a 6 wk period. The excretion of N-acetyl-.beta.-D-glucosaminidase, like the analysis of urinary proteins by disc electrophoresis, is a sensitive parameter for renal damage. The 2 methods were compared, using 50 random urine samples from patients with chronic polyarthritis; both methods had equal diagnostic value.

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