The Effect of Human Serum on 3 H-Thymidine Incorporation in Human Prostate Tumors in Tissue Culture
- 1 June 1978
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 119 (6) , 777-779
- https://doi.org/10.1016/s0022-5347(17)57631-4
Abstract
Human prostatic tumors, 4 adenomas and 4 adenocarcinomas, were established in tissue culture. Incorporation of 3H-thymidine into DNA was used as a measure of cell activity to compare the effects of supplementing the culture media with human or fetal calf serum. 3H-thymidine incorporation was greater with human serum, with up to 120% increase observed. The addition of dihydrotestosterone (10-8M) did not enhance or inhibit 3H-thymidine incorporation.This publication has 16 references indexed in Scilit:
- Effects of Serum on the Growth of Prostatic Cells in VitroJournal of Urology, 1974
- Growth and Hormonal Response of Cells Derived from Carcinoma and Hyperplasia of the Prostate in Monolayer Cell Culture. A Possible in Vitro Model for Clinical ChemotherapyJournal of Urology, 1972
- Human Prostatic Adenocarcinoma: Growth in Monolayer Tissue CultureJournal of Urology, 1971
- Culture of Cells as a Monolayer Derived from the Epithelium of the Human Prostate: A New Cell Growth TechniqueJournal of Urology, 1971
- Quantitative studies on the malignant transformation of mouse prostate cells by carcinogenic hydrocarbonsin vitroInternational Journal of Cancer, 1969
- STUDIES ON ORGAN CULTURE OF HUMAN TUMORS1966
- Action and Interaction of Hormones and 3-Methycholanthrene on the Ventral Prostate Gland of the Rat In Vitro. I. Testosterone and MethylcholanthreneJNCI Journal of the National Cancer Institute, 1965
- The Influence of Stilbestrol and Testosterone on the Growth of Prostatic Adenoma and Carcinoma in Tissue CultureJournal of Urology, 1965
- INFLUENCE OF THE PITUITARY ON PROSTATIC RESPONSE TO ANDROGEN IN THE RAT1955
- Studies on the Growth of Cells. The Cultivation of Bladder and Prostatic Tumors Outside The BodyJournal of Urology, 1917