Synthesis of Epothilones: Stereoselective Routes to Epothilone B
- 1 August 1998
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1998 (8) , 861-864
- https://doi.org/10.1055/s-1998-1794
Abstract
In connection with our studies of the total syntheses of epothilones we report our efforts on the syntheses of epothilone B using a macro-lactonization and a metathesis approach. Key reaction for the solution of the acyclic stereoselection is a stereoselective aldol reaction.Keywords
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