Absent factor II in systemic lupus erythematosus. Immunologic studies and response to corticosteroid therapy
- 1 January 1976
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 19 (1) , 79-82
- https://doi.org/10.1002/art.1780190113
Abstract
This report describes a patient with active systemic lupus erythematosus (SLE) who evidenced severe bleeding consequent to a profound and isolated reduction in plasma factor II (prothrombin) activity. Absence of the factor is documented by immunologic means and its return after corticosteroid therapy is demonstrated. The authors recommend inclusion of this acquired coagulopathy among other more traditional diagnostic manifestations of SLE.This publication has 12 references indexed in Scilit:
- Disorders of hemostatic function in patients with systemic lupus erythematosusSeminars in Arthritis and Rheumatism, 1975
- The Hemostatic Defect Produced by CarbenicillinNew England Journal of Medicine, 1974
- Lupus Erythematosus, Treatment?Annals of Internal Medicine, 1973
- Circulating Anticoagulants Against Factors IX and XI in Systemic Lupus ErythematosusAnnals of Internal Medicine, 1972
- The Specific Assay of Prothrombin Using the Taipan Snake VenomBritish Journal of Haematology, 1971
- REVIEW ARTICLERheumatology, 1971
- Acquired Factor IX Deficiency in the Nephrotic SyndromeAnnals of Internal Medicine, 1970
- Incoagulability of the Blood in Systemic Lupus ErythematosusAmerican Journal of Diseases of Children, 1970
- Plasma Prothrombin during Treatment with DicumarolScandinavian Journal of Clinical and Laboratory Investigation, 1968
- SYSTEMIC LUPUS ERYTHEMATOSUSMedicine, 1954