The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1
Open Access
- 22 January 2008
- journal article
- research article
- Published by Springer Nature in BMC Structural Biology
- Vol. 8 (1) , 3
- https://doi.org/10.1186/1472-6807-8-3
Abstract
The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not well understood. To investigate the mechanisms, we determined the crystal structure of the putative peptide-binding fragment of Hdj1, a human member of the type II Hsp40 family.Keywords
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