Faculty Opinions recommendation of A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
- 10 May 2007
- dataset
- Published by H1 Connect
- Vol. 316 (5829)
- https://doi.org/10.3410/f.1083852.536792
Abstract
As one of three genome-wide studies of type 2 diabetes (T2D) published in this issue {1, 2}, this large Finnish case-control study analyzed >300,000 SNPs to identify genes associated with risk of T2D, and used a second stage sample of case-control study of equal size to genotype an additional 80 SNPs for confirmatory tests. Three recognized genes (TCF7L2 on chr 10, PPARG on chr 3, and KCNJ11 on chr 11) were confirmed in this Finnish...Keywords
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