Proteolipid and Bone Matrix Calcification In Vitro
- 1 August 1977
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 56 (8) , 967-970
- https://doi.org/10.1177/00220345770560082301
Abstract
Proteolipid was demonstrated to contain the nucleator of bone matrix calcification, in vitro. Crude Phospholipid extracted from bone matrix was fractionated by gel filtration. A single, protein-containing fraction induced apatite crystallization in a metastable calcium phosphate solution. The fraction was identified as proteolipid. The result supports the validity of a microbiologic analogue for vertebrate calcification.Keywords
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