Alterations in DMBA-Induced Rat Mammary Tumors by Actinomycin D2
- 1 April 1973
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 50 (4) , 915-920
- https://doi.org/10.1093/jnci/50.4.915
Abstract
Actinomycin D not only protected against the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene, but also influenced the nature of those tumors that developed. Fewer glandular neoplasms, and more secretory adenomas and fibroadenomas were formed. Histologic distinctions among the various mammary nodules are described, and it is stressed that evaluation of experimental data without consideration of the histologic nature of the nodules may be invalid.Keywords
This publication has 0 references indexed in Scilit: