The protease inhibitor leupeptin induces several signs of aging in brain, retina and internal organs of young rats
- 30 June 1991
- journal article
- Published by Elsevier in Archives of Gerontology and Geriatrics
- Vol. 12 (2-3) , 119-131
- https://doi.org/10.1016/0167-4943(91)90023-j
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Anomalous accumulation of τ and ubiquitin immunoreactivities in rat brain caused by protease inhibition and by normal aging: a clue to PHF pathogenesis?Brain Research, 1989
- Development of lipofuscin-like fluorescence in the retinal pigment epithelium in response to protease inhibitor treatmentMechanisms of Ageing and Development, 1989
- The car☐yl third of tau is tightly bound to paired helical filamentsNeuron, 1988
- Inhibitors of Lysosomal Enzymes: Accumulation of Lipofuscin-Like Dense Bodies in the BrainScience, 1984
- Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85Cell, 1984
- Effects of chloroquine on lysosomal enzymes, NADPH-induced lipid peroxidation, and antioxidant enzymes of rat retinaBiochemical Pharmacology, 1983
- Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteinsNature, 1983
- Altered enzyme molecules in senescent organisms: mouse muscle aldolaseMechanisms of Ageing and Development, 1973
- Detection of Inactive Enzyme Molecules in Ageing OrganismsNature, 1970
- BIOLOGICAL ACTIVITIES OF LEUPEPTINSThe Journal of Antibiotics, 1969