Glycemic States and the Horse-Serum and Egg-White Anaphylactic Shock in Rats

Abstract
Summary: The hypoglycemic state produced in rats by 48 hr fasting or by administration of 4 units of insulin aggravated anaphylactic shock when produced by horse serum or egg white, and as measured by per cent mortality, occurrence of lesions in the ileum and hypothermia. Neutralization of the hypoglycemic state by injection of glucose restored the resistance of rats to anaphylactic shock. The degree of hypothermia in anaphylactic shock did not parallel the intensity of the lesions or the per cent mortality.

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