IgM binding to sialosyllactosaminylparagloboside in a patient with polyradiculoneuropathy due toMycoplasma pneumoniaeinfection

Abstract
IgM in serum without paraprotein in a patient with polyradiculoneuropathy due to a Mycoplasma pneumoniae infection reacted specifically with a ganglioside, sialosyllactosaminylparagloboside (SLPG), in a human peripheral nerve on a thin-layer chromatogram plate by an immunostaining technique. This finding suggests the possibility that anti-SLPG antibody in the patient''s serum may play a role in the pathogenesis of neuropathy.