Reactions of Dextrans of Leuconostoc Mesenteroides with the Antiserums of Leuconostoc and of Types 2, 20 and 12 Pneumococcus

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Abstract
Summary: The paper dealt with the serological properties of the polysaccharides isolated from sucrose broth cultures of two strains of Leuconostoc mesenteroides. Chemical data were presented to indicate that the products were dextrans. The serological properties of these dextrans are of particular interest because they represent substances whose production is dependent upon the presence of a particular carbohydrate (sucrose) in the culture medium. The dextrans from both strains reacted not only with the leuconostoc antiserums but also with types 2, 20 and 12 antipneumococcal sera. The most prominent serological difference was that the dextran from one strain was only weakly reactive against the type 12 antiserum in comparison to its reactivity against the types 2 and 20 whereas the dextran from the other (the American Type Culture Collection strain) had approximately the same degree of reactivity against type 12 as against types 2 and 20.

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