Abstract
The minimal concs, of Br and I necessary to inhibit the action of the enzymes were detd. The coagulase of Staphylococcus aureus was supressed by 0.3% conc, of Br and 0.8% I; that of Streptococcus pyogenes was suppressed by 0.2% Br and 0.04% I. Staphylolysin was inhibited by 0.075% Br and 0.4% I while streptolysin was inhibited by 0.02% Br and 0.08% I. The fibrinolysin of Str. pyogenes was inhibited by 0.06% Br and 0.04% I. The spreading factor obtained from testicular extracts (which is identical to the spreading factor obtained from bacteria) was inhibited by 0.2% Br and 0.75% I.

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