EXCESSIVE SELF-ADMINISTERED DOSAGES OF THYROID EXTRACT

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Abstract
A case is reported in which huge doses of thyroid extract were ingested. The total daily dose occasionally exceeded 100 grains of thyroid extract, which the patient took for the concealed purpose of self-destruction. The wt. loss was from 1661/2 lbs. (75.6 kg.), to 80 lbs. (36.3 kg.). Electro-cardiographic study at the height of the thyroid feeding revealed T-waves of definitely decreased amplitude, and as the thyroid was withdrawn, the T-waves increased in amplitude. The patient, prior to death, was in a normal mental state and retained as the only obvious residue, an unstable vascular system, manifested by a sinus tachycardia which developed upon extraordinary activity.
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