The Arterial Spider and Similar Lesions of the Skin and Mucous Membrane

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Abstract
An extensive review is made of the salient clinical features and exptl. studies on arterial spiders noting their association with severe and chronic parenchymal disease of the liver in normal pregnancy. The suggestion is repeated that such changes are caused by steroid hormones with estrogenic activity. The differential diagnosis between such lesions and the venous star, cherry angioma, the cutaneous telangiectases in Osier''s Disease (hereditary hemorrhagic telangiectasia) is emphasized and the clinical characteristics which permit the ready identification and differentiation of such lesions are discussed in detail. Observations were obtained from a series of approx. 1000 patients.

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