Ph chromosome in a patient with non‐leukemic non‐hodgkin B‐cell lymphoma
- 1 November 1990
- journal article
- research article
- Published by Wiley in American Journal of Hematology
- Vol. 35 (3) , 213-215
- https://doi.org/10.1002/ajh.2830350315
Abstract
A standard Philadelphia translocation, t(9;22) (q34;q11), was found in lymph node cells from a patient with non‐leukemic non‐Hodgkin lymphoma at the time of diagnosis. The rearrangement of the breakpoint cluster region (bcr) was not detected with a bcr‐3′ probe. The neoplastic clone was of monoclonal B‐cell character with E‐, CD5‐, CD10‐, CD13‐, CD19+, CD20+, CD21+, CD25‐, HLA DR+, and positive surface lg(kappa). The patient showed no evidence of chronic myelogenous leukemia.Keywords
This publication has 9 references indexed in Scilit:
- Distribution of breakpoint within the breakpoint cluster region (bcr) in chronic myelogenous leukemia with a complex philadelphia chromosome translocationAmerican Journal of Hematology, 1989
- DNA analysis using long-term preserved fixed cytogenetic preparationsJournal of Human Genetics, 1988
- ANALYSIS OF BREAKPOINTS WITHIN THE BCR GENE AND THEIR CORRELATION WITH THE CLINICAL COURSE OF PHILADELPHIA-POSITIVE CHRONIC MYELOGENOUS LEUKEMIA1988
- Analysis of breakpoints within the bcr gene and their correlation with the clinical course of Philadelphia-positive chronic myelogenous leukemiaBlood, 1988
- CHROMOSOME-ABNORMALITIES IN MALIGNANT-LYMPHOMA IN PATIENTS FROM SAITAMA1987
- Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.Proceedings of the National Academy of Sciences, 1986
- Ph Chromosome and B-Cell Malignancy-Associated Chromosomal Aberrations in Non-Leukaemic Immunoblastic B-Cell LymphomaActa Haematologica, 1985
- Recurrent chromosomal defects are found in most patients with non-Hodgkin's-lymphomaCancer Genetics and Cytogenetics, 1984
- Patient with B-cell neoplasia (immunoblastic sarcoma) and the Philadelphia chromosomeCancer Genetics and Cytogenetics, 1983