Mutational analysis of the lambda int gene: DNA sequence of dominant mutations
Open Access
- 30 November 1987
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 169 (12) , 5880-5883
- https://doi.org/10.1128/jb.169.12.5880-5883.1987
Abstract
We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.This publication has 17 references indexed in Scilit:
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