THE PERSISTENCE OF HEMOPOIETIC STEM CELLS IN VITRO
Open Access
- 1 February 1973
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 56 (2) , 429-433
- https://doi.org/10.1083/jcb.56.2.429
Abstract
Cells capable of forming colonies in spleens of irradiated mice (CFU) are lost temporarily when bone marrow cells from rats or mice are maintained in culture. Rat marrow CFU go through a minimum at about 3 days after which there is a slow increase in the number of CFU in culture, reaching a maximum at 9 days. Mouse marrow CFU reach a minimum at 3 days and a maximum at 7 days. Some rat marrow CFU persist in culture for as long as 28 days.Keywords
This publication has 12 references indexed in Scilit:
- Protein Synthesis: Its Control in ErythropoiesisScience, 1972
- On the mechanism of erythropoietin-induced differentiation. IX. Induced synthesis of 9 S ribonucleic acid and of hemoglobin.1971
- Kinetics of Haemopoietic Colony GrowthBritish Journal of Haematology, 1971
- Effect of Steroids on the Cycling of Haemopoietic Stem CellsNature, 1970
- Evidence for the existence of multipotential lympho-hematopoietic stem cells in the adult ratJournal of Cellular Physiology, 1970
- Mechanism of erythropoietin-induced differentiation. V. Characterization of the ribonucleic acid formed as a result of erythropoietin actionBiochemistry, 1969
- In vitro behavior of stem cells.1968
- The effects of erythropoietin on haem synthesis in mouse yolk sac and cultured foetal liver cellsDevelopment, 1966
- The Effect of Erythropoietin upon Heme Synthesis by Marrow Cells in VitroJournal of Biological Chemistry, 1963
- Cytological Demonstration of the Clonal Nature of Spleen Colonies Derived from Transplanted Mouse Marrow CellsNature, 1963