A SENSITIVE HUMAN THYROGLOBULIN RIA TO DEFINE CLEARLY THE PRESENCE OR ABSENCE OF FUNCTIONING THYROID-TISSUE

  • 1 January 1984
    • journal article
    • research article
    • Vol. 25  (1) , 49-55
Abstract
A practical procedure to establish a sensitive radioimmunoassay for the measurement of human thyroglobulin (HTg) in serum is described. The assay enables a clear distinction to be made between levels of HTg indicating the presence or absence of functioning thyroid tissue. It compares the use of HTg serum levels with the conventional I-131 scintigram as a marker for recurrent thyroid cancer. A simple and sensitive radioimmunologic assay is described for the determination of serum antithyroglobulin autoantibodies, the presence of which may give falsely elevated HTg levels.

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