THE EFFECT OF OESTROGEN AND THYROXINE ON THE BLOOD VOLUME OF THE DOMESTIC COCK

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Abstract
SUMMARY: The influence of thyroxine and oestrogen on blood, plasma and erythrocyte volumes of the domestic fowl was investigated. During the 1st week of oestrogen treatment the haematocrit values, erythrocyte and blood volumes decreased significantly. After 2 weeks, plasma volume increased, blood volume returned to normal, and erythrocyte volume remained at its previously low value. The simultaneous injection of thyroxine with oestrogen prevented these changes, and in this respect thyroxine is antagonistic to oestrogen. The significance of these results is discussed in relation to the possible mode of action of these two hormones.