Maintenance of transposon-free regions throughout vertebrate evolution
Open Access
- 20 December 2007
- journal article
- research article
- Published by Springer Nature in BMC Genomics
- Vol. 8 (1) , 470
- https://doi.org/10.1186/1471-2164-8-470
Abstract
We recently reported the existence of large numbers of regions up to 80 kb long that lack transposon insertions in the human, mouse and opossum genomes. These regions are significantly associated with loci involved in developmental and transcriptional regulation.Keywords
This publication has 33 references indexed in Scilit:
- Thousands of human mobile element fragments undergo strong purifying selection near developmental genesProceedings of the National Academy of Sciences, 2007
- Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesNature, 2007
- Ensembl 2007Nucleic Acids Research, 2006
- Alu elements as regulators of gene expressionNucleic Acids Research, 2006
- A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem CellsCell, 2006
- Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomesGenome Research, 2005
- Role of transposable elements in heterochromatin and epigenetic controlNature, 2004
- The UCSC Genome Browser DatabaseNucleic Acids Research, 2003
- Initial sequencing and comparative analysis of the mouse genomeNature, 2002
- Initial sequencing and analysis of the human genomeNature, 2001