Gene Transfer of Endothelial Nitric Oxide Synthase Reduces Angiotensin II–Induced Endothelial Dysfunction
- 1 February 2000
- journal article
- other
- Published by Wolters Kluwer Health in Hypertension
- Vol. 35 (2) , 595-601
- https://doi.org/10.1161/01.hyp.35.2.595
Abstract
—Angiotensin II stimulates vascular NADPH oxidase to produce superoxide, which can react with nitric oxide and impair vasomotor function. We tested the hypothesis that the overexpression of...Keywords
This publication has 19 references indexed in Scilit:
- Validation of Lucigenin as a Chemiluminescent Probe to Monitor Vascular Superoxide as Well as Basal Vascular Nitric Oxide ProductionBiochemical and Biophysical Research Communications, 1999
- Expression and Function of Recombinant Endothelial Nitric Oxide Synthase Gene in Canine Basilar ArteryCirculation Research, 1997
- Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.Journal of Clinical Investigation, 1996
- Chronic infusion of low-dose angiotensin II potentiates the adrenergic response in vivoJournal Of Hypertension, 1996
- Kinetics of Cytochrome C2+ Oxidation by Peroxynitrite: Implications for Superoxide Measurements in Nitric Oxide-Producing Biological-SystemsArchives of Biochemistry and Biophysics, 1995
- Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aortaEuropean Journal of Pharmacology, 1994
- Hypercholesterolemia increases endothelial superoxide anion production.Journal of Clinical Investigation, 1993
- Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries.Hypertension, 1992
- Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factorNature, 1986
- Extracellular superoxide dismutase in human tissues and human cell lines.Journal of Clinical Investigation, 1984