Linear solvation energy relationship. Part 11. An analysis of nitrogen-15 solvent shifts in amides
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 2
- No. 2,p. 353-355
- https://doi.org/10.1039/p29810000353
Abstract
The solvatochromic comparison method is used to unravel and rationalize solvent effects on the 15N n.m.r. spectra of some N-unsubstituted, N-monoalkyl-, and NN-dialkyl-amides. It is shown that, in addition to solvent polarity–polarizability and type-A hydrogen bonding effects, type-B hydrogen bonding by the second protons of self-associated formamide leads to a significant dependence of the 15N shifts on solvent β values. In the case of the N-monoalkylamides, however, self association is sufficiently strong that the dependence of the shifts on solvent β values is negligible.Keywords
This publication has 0 references indexed in Scilit: