AN EVALUATION OF THE GUTERMAN PREGNANCY TEST IN CLINICAL PRACTICE1

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Abstract
THE evaluation of the Guterman pregnancy test here reported has two distinct features: In the first place, we have resisted the temptation to modify the technique and have used it as described by its sponsor (4, 5) Secondly, we have employed the procedure routinely and have avoided a “test-series” of cases. The selection of patients has been entirely in the hands of the house and attending staffs; when it was clinically necessary to determine whether or not a patient was pregnant by laboratory methods, this test was performed, although a Friedman test would also be carried out on request. By this means we have gained a more accurate estimate of the usefulness of the test for hospital and dispensary practice. The technique outlined by Guterman employs the color reaction of Talbot et at. (9) and a modification of the extraction method of Astwood and Jones (1). Essentially it amounts to a qualitative reading of a quantitative change, and is based on the assumption that amenorrhea plus 1 mg. pregnandiol per 100 cc. urine occurs only with pregnancy and always with pregnancy.

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