INHIBITORY EFFECT OF ANALOGUES OF PHENYLARSONATE ON PURIFIED 19S AND 7S ANTIBODIES SPECIFIC FOR AZOPHENYLARSONATE

  • 1 January 1967
    • journal article
    • research article
    • Vol. 12  (2) , 219-+
Abstract
Purified 19S and 7S antibodies specific for protein-conjugated azophenylarsonate were compared with respect to their affinities for the free haptens, phenylarsonate and the o-, m- and p-isomers of mononitrophenylarsonate, as judged from the technique of inhibition of haemagglutination of cells conjugated with the hoologous hapten. It was found that the 2 antibody types were equally effective in discriminating among the isomeric haptens, but that 7S antibody was consistently more readily inhibited than the 19S by all the haptens tested. Various parameters concerning agglutination and its inhibition are discussed with regard to these 2 antibody forms.