Reactivity of the limulus lysate assay with uterine cervical secretions. A preliminary evaluation.

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Abstract
A Limulus lysate assay was performed on cervical secretions from 66 women. When secretions were tested at a 1/100 dilution the assay gave a positive result in 15 (62.5%) of 24 patients with gonorrhea confirmed by Gram-stained smear or culture or both. When secretions from 7 of the 9 remaining patients who had gonorrhea but negative results to the Limulus lysate test were retested at a 1/50 dilution, 2 gave a positive result, increasing the positivity rate of the test to 17 (70.8%) of 24 infected patients. Material from 1 patient with a history of contact with gonorrhea and from 3 (7.3%) of the other 41 patients with no history of gonorrhea gave positive reactions.

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