Increased Detection of Occult Breast Carcinoma after More Thorough Histologic Examination of Breast Biopsies

Abstract
Six cases of occult carcinoma of the breast were detected by histologic examination of 244 consecutive grossly benign breast biopsies (2.4%). Half of the cancers were found in a routine random sample of ten tissue blocks, while the others were detected only after the entire biopsy was examined. The detection of the additional cases appeared directly related to the amount of tissue examined microscopically. More complete histologic examination of breast biopsies appears indicated to detect occult breast cancer.

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