An efficient method for labelling antibodies with 111In
- 23 January 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 166 (1) , 202-204
- https://doi.org/10.1016/0014-5793(84)80073-3
Abstract
Using a new method, rabbit IgG and a monoclonal antibody have been conjugated with the chelating agent DTPA. This was accomplished with reaction conditions that should entail lower antibody damage than existing methods. Gel filtration of the 111In‐labelled antibody conjugate indicated minimal damage to the antibody and radioimmunoassay showed no significant change in its immunological activity.Keywords
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