Acute Poisoning by Intentional Ingestion of Thallous Malonate

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Abstract
1 A 26-year-old man who ingested 10 g of thallous malonate was treated by gastric lavage and combined haemodialysis and haemoperfusion. 2 At a blood flow of 100 ml/min, the average of thallium clearance values obtained by combined haemoperfusion and haemodialysis at two different times were 50.2 and 60.4 ml/min. 3 Forty hours after ingestion, he died of cardiac failure. A higher concentration of thallium was found in the heart than in other organs, suggesting that the heart is the main target of thallium in the early stage of acute poisoning.