Inappropriate Antidiuretic Hormone

3 April 1978

journal article
research article
Published by American Medical Association (AMA)

Vol. 239 (14) , 1422-1423
https://doi.org/10.1001/jama.1978.03280410064025

Abstract

SINCE first described by Schwartz et al¹in 1957, the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) has been recognized in a variety of pathologic processes. Its appearance as an untoward effect of therapeutic agents has recently been reviewed by Miller and Moses.²We report what we believe to be the first such case of SIADH secondary to a monamine oxidase inhibitor. Report of a Case A 66-year-old man was admitted to the Shands Teaching Hospital for the first time in August 1976 for severe depression. During the previous 18-month period, he had been treated with two courses of electroconvulsive shock therapy and various antidepressants, with only minimal improvement followed by relapse to his previous level of depression. Results of the physical examination showed a blood pressure of 150/90 mm Hg and a pulse rate of 80 beats per minute. The neck veins were flat and there

Keywords

This publication has 1 reference indexed in Scilit:

Drug-induced states of impaired water excretion
Kidney International, 1976