Synthesis of conformationally restricted analogs of kainic acid. Is the conformation of the C4-substituent of kainoid important to its neuroexcitatory activity?

This publication has 16 references indexed in Scilit:

• Conformational feature of neuroactive domoic acid: X-ray structural comparison with isodomoic acid A and α-kainic acid
  Biochemical and Biophysical Research Communications, 1992
• Configurational variants of hydroxyphenylkainoid: their potent depolarizing activities in the rat central nervous system
  Bioorganic & Medicinal Chemistry Letters, 1992
• Novel kainate derivatives: potent depolarizing actions on spinal motoneurones and dorsal root fibres in newborn rats
  British Journal of Pharmacology, 1991
• Synthesis of new acromelic acid congeners: novel neuroexcitatory amino acids acting on glutamate receptor
  Tetrahedron Letters, 1991
• Simple analogs of acromelic acid, which are highly active agonists of kainate type neuroexcitant
  Tetrahedron Letters, 1990
• Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists
  Trends in Pharmacological Sciences, 1990
• Syntheses of acyclic analogues of kainoids and neuroexcitatory activity
  Tetrahedron Letters, 1989
• Trans-2-carboxy-3-pyrrolidineacetic acid (CPAA), a novel agonist at NMDA-type receptors
  Neuroscience Letters, 1988
• Structure of Kainic Acid and its Isomer, Allokainic Acid
  Nature, 1958
• The Structure of Kainic Acid, the Most Active Component of Digenea simplex Ag. I. The Molecular and Crystal Structure of Zinc Kainate Dihydrate
  Bulletin of the Chemical Society of Japan, 1957