Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

This publication has 51 references indexed in Scilit:

• Differentiating the functional role of hypoxia‐inducible factor (HIF)‐1α and HIF‐2α (EPAS‐1) by the use of RNA interference: erythropoietin is a HIF‐2α target gene in Hep3B and Kelly cells
  The FASEB Journal, 2004
• Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth
  PLoS Biology, 2003
• Targeting HIF-1 for cancer therapy
  Nature Reviews Cancer, 2003
• Hypoxia-Induced Gene Expression Occurs Solely through the Action of Hypoxia-Inducible Factor 1α (HIF-1α): Role of Cytoplasmic Trapping of HIF-2α
  Molecular and Cellular Biology, 2003
• Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
  Nature, 2002
• Hypoxia — a key regulatory factor in tumour growth
  Nature Reviews Cancer, 2002
• Role of transforming growth factor-alpha in von Hippel- Lindau (VHL)-/- clear cell renal carcinoma cell proliferation: A possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis
  Proceedings of the National Academy of Sciences, 2001
• Mechanism of regulation of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor protein
  The EMBO Journal, 2000
• Cellular and developmental control of O₂ homeostasis by hypoxia-inducible factor 1α
  Genes & Development, 1998
• Cancer Cell Cycles
  Science, 1996