Incorporation of [U-13C]glycerol defines plausible early steps for the biosynthesis of methylenomycin A in Streptomyces coelicolor A3(2)
- 2 May 2001
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 10,p. 935-936
- https://doi.org/10.1039/b101615f
Abstract
Incorporation of [U-13C]glycerol into the linear plasmid-encoded secondary metabolite methylenomycin A, both intact and indirectly via metabolism to acetyl CoA, was observed in Streptomyces coelicolor suggesting plausible early biosynthetic steps for this unusual antibiotic.Keywords
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