Attempts to infect small laboratory animals with the infective larvae of Onchocerca lienalis
- 1 December 1981
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of Helminthology
- Vol. 55 (4) , 247-249
- https://doi.org/10.1017/s0022149x00027814
Abstract
All the natural hosts of Onchocerca parasites are large animals (MULLI-R, 1979) andthere is, therefore an urgent need to develop a small animal model for onchoccrciasis,preferably one that employs a strain of inbred host. Rodents have been usedsuccessfully as experimental hosts for the microfilariac of O. guiturosa (sec NELSON et al. 1966), O. cervicalis (see RAbalais, 1974), O. armilluta (see EL Bihari & Hussein, 1975) and O. ijibsoni (see Beveridge et al., 1980) but there have been few publishedattempts to infect these hosts with infective-stage larvae.Keywords
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