A Simple Diagnostic Test for Pupillary Abnormality in Diabetic Autonomic Neuropathy
- 1 January 1986
- journal article
- Published by Wiley in Diabetic Medicine
- Vol. 3 (1) , 38-41
- https://doi.org/10.1111/j.1464-5491.1986.tb00703.x
Abstract
A simple portable pupillometer using Polaroid photography has been developed for use in the diagnosis of diabetic autonomic neuropathy. The pupil diameter per cent (PD%), defined as the percentage of iris diameter to which pupil diameter had dilated in darkness, was measured from the instant colour prints. An age‐related normal range was constructed from measurements in 163 healthy subjects in whom PD% declined linearly by 3% per decade. The PD% was measured in 15 patients with automatic neuropathy and 12 were identified with abnormally low values indicating a failure of sympathetically mediated dilatation. Results were consistent with the standard television pupillometric technique and had the same high repeatability with a coefficient of variation of 3.2%.Keywords
This publication has 12 references indexed in Scilit:
- Autonomic Neural Dysfunction in Recently Diagnosed Diabetic SubjectsDiabetes Care, 1984
- Use of a biothesiometer to measure individual vibration thresholds and their variation in 519 non-diabetic subjects.BMJ, 1984
- Reduced pupillary light reflexes in diabetic autonomic neuropathyDiabetologia, 1983
- Evidence for a neuropathic aetiology in the small pupil of diabetes mellitus.British Journal of Ophthalmology, 1983
- Reduced sinus arrhythmia in diabetic autonomic neuropathy: diagnostic value of an age-related normal range.BMJ, 1982
- Diagnosis and management of diabetic autonomic neuropathy.BMJ, 1982
- Cardiac autonomic dysfunction in patients with diabetic retinopathyDiabetologia, 1981
- Heart Rate Variability in Healthy Subjects Measured with a Bedside Computer-Based TechniqueClinical Science, 1981
- Pupil motility in long-term diabetesDiabetologia, 1979
- Pupillary signs in diabetic autonomic neuropathy.BMJ, 1978