Integration of gene maps: updating chromosome 1
- 1 July 1995
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 59 (3) , 291-305
- https://doi.org/10.1111/j.1469-1809.1995.tb00749.x
Abstract
SUMMARY: The first integrated map of chromosome 1 was published in 1992. We present an updated summary map of 371 loci constructed from a location database that includes physical and genetic data. The summary map subsumes a composite physical location, sex‐specific genetic location, cytogenetic assignment, mouse homology, rank and references to physical maps. The genetic length is 208 cM for the male map, in close agreement with the chiasma map, and 371 cM for the female map. There is evidence for a high level of interference on chromosome 1. The location database comprising both data and analytical software is discussed in relation to alternative approaches and possible enhancements.Keywords
This publication has 31 references indexed in Scilit:
- The 1993–94 Généthon human genetic linkage mapNature Genetics, 1994
- Integrated human genome–wide maps constructed using the CEPH reference panelNature Genetics, 1994
- Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage mapNature Genetics, 1994
- CEPH Consortium Map of Chromosome 9Genomics, 1994
- Physical Mapping of a Functional Cluster of Epidermal Differentiation Genes on Chromosome 1q21Genomics, 1993
- Construction of a physical map on mouse and human chromosome 1: comparison of 13 Mb of mouse and 11 Mb of human DNAHuman Molecular Genetics, 1992
- Algorithms for a location databaseAnnals of Human Genetics, 1992
- Guidelines for human linkage maps An International System for Human Linkage Maps (ISLM, 1990)Annals of Human Genetics, 1991
- Standard maps of chromosome 10Annals of Human Genetics, 1990
- MAP, an expert system for multiple pairwise linkage analysisAnnals of Human Genetics, 1989