STUDIES ON FAT METABOLISM. III. LIPEMIA INDUCED BY INTRAVENOUS FAT ADMINISTRATION*

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Abstract
Emulsion of egg yolk injected intravenously into dogs disappeared from the blood much more slowly than fat absorbed from the intestine. Starvation, insulin, pituitrin, suprarenalin, thyroid, parathormone, secretin, cholecystokinin, bile salts did not affect rate of removal. Glucose delayed removal. Removal was slower in pancreatectomized dogs and was hastened by insulin. Eck fistula dogs had similar lipemia curves. Apparently a hormonal mechanism is not concerned, but the intestinal mucosa acts on the fat and renders it more easily taken up by the tissues.

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