Localized Cooling in the Central Nervous System

Publisher Website
Google Scholar
Abstract
Introduction The recent progress in clinical stereotactic surgery has largely been the result of detailed human brain atlases, effective procedures for making discrete brain lesions, and improved lightweight accurate stereotactic machines. These advances rely on the correlation of neuroanatomical landmarks with the radiographic ventricular outline. The individual variations in human brains plus the necessity of translating ventriculothalamic measurements obtained from the cadaver to the living patient give less than perfect accuracy in placing a stereotactic lesion within the cerebral target area. This is particularly true when the target area lies in the thalamus of a patient with infantile choreoathetosis, since diffuse brain pathology often distorts the relation of the target area to ventricular landmarks. In this situation, the necessity of using neurophysiological guides is apparent. Stimulation, recording of evoked potentials, and the production of reversible brain lesions have been the three standard physiological guides used by stereotactic surgeons. Our group

This publication has 4 references indexed in Scilit: