Behaviour of Different Enzyme Activities in the Lenses of Chickens during the First Year of Life

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Abstract
In 110 experiments 314 lenses from 4 to 361-day-old chickens were biochemically studied and enzyme activities of Lactate-dehydrogenase (LDH), Malate-dehydrogenase (MDH), NAD-depending-Sorbitol-dehydrogenase (SDH), Fructo-aldolase (ALD), Glucose-6-phosphat-dehydrogenase (G-6-PDH), Glutamate-oxalacetate-transaminase (GOT) and Glutamate-pyruvate-transaminase (GPT) were measured. Results were evaluated by factor analysis. The interpretation of this biostatistical procedure could be assured by additional experiments. Furthermore it is investigated, whether the possibilities of factor analysis and its interpretation permit a relation of the age-dependent sensibility of the lens to X-irradiation. It could be shown, that mostly the metabolism of growth is influenced by ionising radiation, and that as a shift to the metabolism of older lenses. Finally this interpretation is examined by investigations of irradiation influence on the latency period of galactose cataracts in rats.

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