Reactivity of Purified Proteins and Polysaccharides from Mycobacterium tuberculosis in Delayed Skin Test and Cultured Lymphocyte Mitogenesis Assays
- 1 January 1974
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 9 (1) , 44-47
- https://doi.org/10.1128/iai.9.1.44-47.1974
Abstract
Hypersensitivity responses to two highly purified and well characterized mycobacterial proteins and a preparation of mycobacterial arabinogalactanarabinomannan were studied by using guinea pig skin tests and in vitro-cultured human lymphocyte mitogenesis stimulation assays. The purified proteins were found to elicit delayed-type hypersensitivity skin test reactions and to stimulate mitogenesis in cultured lymphocytes. The polysaccharide preparation was found to evoke delayed skin tests but not to stimulate cultured lymphocytes.Keywords
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