High-level expression of interleukin-4 following electroporation-mediated gene transfer accelerates Type 1 diabetes in NOD mice
- 31 March 2003
- journal article
- Published by Elsevier in Journal of Autoimmunity
- Vol. 20 (2) , 111-117
- https://doi.org/10.1016/s0896-8411(03)00004-0
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 23 references indexed in Scilit:
- Biolistic-Mediated Interleukin 4 Gene Transfer Prevents the Onset of Type 1 DiabetesHuman Gene Therapy, 2000
- Acceleration of Autoimmune Diabetes by Cyclophosphamide is Associated with an Enhanced IFN-γ Secretion PathwayJournal of Autoimmunity, 1999
- Local Expression of TNFα in Neonatal NOD Mice Promotes Diabetes by Enhancing Presentation of Islet AntigensImmunity, 1998
- INDUCTION OF TH1 AND TH2 CD4+T CELL RESPONSES:The Alternative ApproachesAnnual Review of Immunology, 1997
- Demonstration of a TH1cytokine profile in the late phase of NOD insulitisCytokine, 1995
- In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.Journal of Clinical Investigation, 1995
- T Helper Cell Subsets in Insulin-Dependent DiabetesScience, 1995
- Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice.The Journal of Experimental Medicine, 1995
- Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.The Journal of Experimental Medicine, 1993
- The involvement of Ly 2+ T cells in beta cell destructionJournal of Autoimmunity, 1990