Lipoprotein concentrations in normolipidemic males consuming oleic acid-rich diets from two different sources: olive oil and oleic acid-rich sunflower oil
Open Access
- 1 October 1995
- journal article
- clinical trial
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 62 (4) , 769-775
- https://doi.org/10.1093/ajcn/62.4.769
Abstract
The effects on plasma lipid concentrations of two oleic acid-rich diets, prepared with two different plant oils--olive oil and sunflower oil high in monounsaturated fatty acids (MUFAs)-- were compared with a National Cholesterol Education Program (NCEP) I diet. Twenty-one healthy, normolipidemic, young males consumed an NCEP-I diet (30% of energy as fat) during a 25-d period. Subjects were then assigned to two 4-wk study periods, according to a randomized, crossover design. Group one was placed on an olive oil-enriched diet (40% fat, 22% MUFAs), followed by a 4-wk period of a sunflower oil-enriched diet (40% fat, 22% MUFAs). In group two, the order of the diets was reversed. Both MUFA dietary periods resulted in an increase in high-density-lipoprotein (HDL) cholesterol (7% for the olive oil diet and 4% for the sunflower oil diet) and in apolipoprotein (apo) A-I (9% for both) compared with the NCEP-I diet. Low-density-lipoprotein (LDL) cholesterol and apo B concentrations (x +/- SEM) were lower (P < 0.05) during the sunflower oil diet (2.40 +/- 0.11 mmol/L, 0.85 +/- 0.04 mg/L) than during the olive oil diet (2.64 +/- 0.15 mmol/L, 0.93 +/- 0.05 mg/L). No significant differences were observed in these variables between the sunflower oil and NCEP-I (2.48 +/- 0.13 mmol/L, 0.89 +/- 0.04 mg/L) diets.(ABSTRACT TRUNCATED AT 250 WORDS)Keywords
This publication has 29 references indexed in Scilit:
- Treatment of severe familial hypercholesterolemia in childhood with sitosterol and sitostanolThe Journal of Pediatrics, 1993
- Effects of Stigmasterol-Supplemented Diets on Fecal Neutral Sterols and Bile Acid Excretion in RatsAnnals of Nutrition and Metabolism, 1989
- Effect of gender, age, and lipid status on low density lipoprotein subfraction distribution. Results from the Framingham Offspring Study.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1987
- Immunoturbidimetric determination of apolipoproteins A-1 and B in serumScandinavian Journal of Clinical and Laboratory Investigation, 1987
- Comparison of Monounsaturated Fatty Acids and Carbohydrates for Lowering Plasma CholesterolNew England Journal of Medicine, 1986
- Plant sterols as cholesterol-lowering agents: Clinical trials in patients with hypercholesterolemia and studies of sterol balanceAtherosclerosis, 1977
- THE INFLUENCE OF DIET ON SERUM-TRIGLYCERIDESThe Lancet, 1961
- PREDICTION OF SERUM-CHOLESTEROL RESPONSES OF MAN TO CHANGES IN FATS IN THE DIETThe Lancet, 1957
- The Effect of Beta Sitosterol on the Serum Lipids of Young Men with Arteriosclerotic Heart DiseaseCirculation, 1956
- Successful Prevention of Experimental Hypercholesteremia and Cholesterol Atherosclerosis in the RabbitCirculation, 1953