Pesticides: Insecticides and Fungicides Are Chitin Synthesis Inhibitors
- 21 August 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4510) , 905-907
- https://doi.org/10.1126/science.213.4510.905
Abstract
Several important groups of fungicides and insecticides are specific inhibitors of chitin synthesis in a Phycomyces enzyme system and in insect organ cultures. The recently discovered benzoylphenylurea insecticides, which prevent chitin synthesis in insect tissues, are apparently not direct-acting chitin synthetase inhibitors. These insecticides may prevent insect chitin synthesis by interfering with the proteolytic activation of the chitin synthetase zymogen.Keywords
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