Abstract
Disseminated lesions of the central nervous system may be inflammatory (encephalomyelitis), acute or subacute degenerative (multiple degenerative softening), chronic degenerative (multiple sclerosis) and neoplastic (multiple tumors). Of the aforementioned, the best studied is the chronic degenerative form known as multiple sclerosis. Disseminated inflammatory (nonsyphilitic) lesions are less known; subacute degenerative lesions (multiple degenerative softening) are commonly referred to as acute or malignant multiple sclerosis, while disseminated cerebrospinal tumors are exceptionally rare and, for this reason, are not considered in the differential clinical diagnosis. Disregarding for the moment the last type, I shall record here my observations on the disseminated inflammatory type of lesions of the central nervous system and contrast them with the changes occurring in multiple sclerosis and multiple degenerative softening. REPORT OF A CASE A white woman aged 43 was admitted to the Research and Educational Hospitals on July 16, 1936, because of paralysis of the lower extremities

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