RHEUMATOID-ARTHRITIS AND LYMPHOCYTE-B ALLOANTIGEN HLA-DRW4

  • 1 January 1980
    • journal article
    • research article
    • Vol. 7  (1) , 9-12
Abstract
Forty Caucasian patients with classical or definite rheumatoid arthritis were tested for 7 HLA-DR alloantigens and 37 HLA-A, B and C antigens and compared with 125 and 450 healthy controls, respectively. HLA-DRw4 was significantly (corrected P = 10-3) increased in rheumatoid arthritis (55%) compared with controls (23%). There was no significant correlation between clinical, radiological or serological disease parameters and HLA-DRw4. The frequency of HLA-B8 was increased in the patient group; the corrected P value was not significant.